A systematic review and meta-analysis of blood level of MCP-1/CCL-2 in severe and uncomplicated malaria

Manas Kotepui, Pattamaporn Kwankaew, Aongart Mahittikorn, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Apichai Wattanapisit, Polrat Wilairatana · 2024

Read A systematic review and meta-analysis of blood level of MCP-1/CCL-2 in severe and uncomplicated malaria by Manas Kotepui, Pattamaporn Kwankaew, Aongart Mahittikorn, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Apichai Wattanapisit, Polrat Wilairatana (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11579328.txt.

Description

Manas Kotepui and co-authors review in 2024 blood levels of a signal protein in malaria, from mild to severe cases. The protein draws white cells to sites of swelling and may track how bad the illness is. The team pools past studies to weigh that link.

Thirty three studies with six thousand eight hundred four people enter the review. Most came from Africa and dealt with the main malaria type. Pooled checks found no clear gap in protein levels between sick and well groups. Levels also failed to split severe from mild cases in a firm way. The team flags wide spread across studies.

Catalog record

CREATORManas Kotepui, Pattamaporn Kwankaew, Aongart Mahittikorn, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Apichai Wattanapisit, Polrat Wilairatana
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11579328

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