Sex hormones and reproductive factors with cardiac arrhythmia and ECG indices: a mendelian randomization study
Xishu Wang, Zhaoyang Wei, Zheng Zuo, Ying Sun, Xiaoxue Guo, Yi Tong, Guanghui Liu, Dongyang Xu, Zhiguo Zhang · 2024
Read Sex hormones and reproductive factors with cardiac arrhythmia and ECG indices: a mendelian randomization study by Xishu Wang, Zhaoyang Wei, Zheng Zuo, Ying Sun, Xiaoxue Guo, Yi Tong, Guanghui Liu, Dongyang Xu, Zhiguo Zhang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11577811.txt.
Description
Xishu Wang and co-authors report a 2024 gene-based study on sex hormones, reproductive factors, and heart rhythm disorders. Sex shapes who gets rhythm trouble and why, and hormones look like part of the cause, yet plain observation cannot prove it. A method that uses genes as a stand-in for hormone levels can test cause with less bias.
The team drew hormone data from a large UK gene bank, split by sex, and rhythm and heart trace data from a Finnish group and other big studies. In men, genes for higher levels of one female hormone linked to lower risk of a common rhythm disorder. Genes for higher total male hormone linked to lower heart rate variability. No links showed for other rhythm disorders or trace measures in men. In women, no clear links showed at all.
Catalog record
| CREATOR | Xishu Wang, Zhaoyang Wei, Zheng Zuo, Ying Sun, Xiaoxue Guo, Yi Tong, Guanghui Liu, Dongyang Xu, Zhiguo Zhang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |