Cellular senescence in Alzheimer’s disease: from physiology to pathology
Jing Zhu, Chongyun Wu, Luodan Yang · 2024
Read Cellular senescence in Alzheimer’s disease: from physiology to pathology by Jing Zhu, Chongyun Wu, Luodan Yang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11577763.txt.
Description
Jing Zhu, Chongyun Wu, and Luodan Yang review the role of cellular senescence, the state in which cells stop dividing, in Alzheimer disease, in a 2024 paper. The disease is marked by amyloid buildup and tangled tau protein, yet drugs aimed at those marks have not yielded strong treatments. Attention has turned to aging cells as a driver of decline.
The review sums up what senescent cells do in health, their traits and markers, and the models used to study them. It walks through senescence in five brain cell types, from support cells to neurons. It closes with treatment ideas that clear or calm such cells, and the factors that push brain cells into that state.
Catalog record
| CREATOR | Jing Zhu, Chongyun Wu, Luodan Yang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 73 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |