Comparation of two cystatin C-based eGFR equations in assessing risk of all-cause mortality and incident cardiovascular disease

Guangda Xin, Qianyu Li, Chen Sheng, Yining Zha, Kailiang Cheng · 2024

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Description

Guangda Xin and four co-authors compared two kidney function formulas head to head in a 2024 study of Chinese adults. Both formulas estimate filtration rate from cystatin C, a blood marker: one from the CKD-EPI group in 2021, one from a European consortium in 2023. The team followed 6,496 adults from a national aging study for up to seven years, logging 473 deaths and 1,996 new cardiovascular cases.

Low estimated function by the CKD-EPI formula, below sixty units, came with clearly higher risks of death and of new heart and vessel disease. The European formula's levels, by contrast, showed no significant link to either outcome. The authors recommend the CKD-EPI cystatin C equation for risk tracking in this population, while calling for more validation.

Catalog record

CREATORGuangda Xin, Qianyu Li, Chen Sheng, Yining Zha, Kailiang Cheng
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11577579

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