Development of selective ssDNA micro-probe for PD1 detection as a novel strategy for cancer imaging

Stanisław Malicki, Anna Czarna, Edyta Żyła, Barbara Pucelik, Wojciech Gałan, Barbara Chruścicka, Marta Kamińska, Alicja Sochaj-Gregorczyk, Katarzyna Magiera-Mularz, Jun Wang, Marek Winiarski, Małgorzata Benedyk-Machaczka, Joanna Kozieł, Grzegorz Dubin, Piotr Mydel · 2024

Read Development of selective ssDNA micro-probe for PD1 detection as a novel strategy for cancer imaging by Stanisław Malicki, Anna Czarna, Edyta Żyła, Barbara Pucelik, Wojciech Gałan, Barbara Chruścicka, Marta Kamińska, Alicja Sochaj-Gregorczyk, Katarzyna Magiera-Mularz, Jun Wang, Marek Winiarski, Małgorzata Benedyk-Machaczka, Joanna Kozieł, Grzegorz Dubin, Piotr Mydel (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11576874.txt.

Description

Stanislaw Malicki leads a team that builds a DNA probe for a cell mark. Their work from twenty twenty-four deals with PD1, a mark on worn out immune cells. Tracking PD1 could help spot cancer and immune disease.

The team picked a short DNA strand that binds PD1 well. They trimmed it, checked its strength, and made it glow. Tests used human cells with extra PD1 and mouse organ models. The probe lit up cells that bore the mark, even in mixed groups. It may one day serve as a scan tool.

Catalog record

CREATORStanisław Malicki, Anna Czarna, Edyta Żyła, Barbara Pucelik, Wojciech Gałan, Barbara Chruścicka, Marta Kamińska, Alicja Sochaj-Gregorczyk, Katarzyna Magiera-Mularz, Jun Wang, Marek Winiarski, Małgorzata Benedyk-Machaczka, Joanna Kozieł, Grzegorz Dubin, Piotr Mydel
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11576874

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