Biomarkers of systemic treatment response: MR images of intratumoral fat deposition in colorectal liver metastases (CRLM) after chemotherapy
Irmina Morawska, Katarzyna Pasicz, Andrzej Cieszanowski · 2024
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Description
When colon cancer spreads to the liver, fat showing up inside the tumors after chemotherapy may carry news about how a patient will fare. Irmina Morawska, Katarzyna Pasicz, and Andrzej Cieszanowski looked back at scans from ninety-eight patients treated between twenty seventeen and twenty twenty-two. A special MRI method flags fat when the signal drops by at least twelve percent between two kinds of image.
No patient showed tumor fat before treatment, but twenty-nine did afterward, close to thirty percent. Those patients lived a median of thirty-two months, against forty-eight months for patients whose tumors stayed fat-free. The team concludes that fat appearing in these liver tumors after treatment is a warning sign tied to a poorer outlook.
Catalog record
| CREATOR | Irmina Morawska, Katarzyna Pasicz, Andrzej Cieszanowski |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |