Arterial Occlusive Events in a Patient With Chronic Myeloid Leukemia Treated With Ponatinib
Osamu Imataki, Makiko Uemura · 2024
Read Arterial Occlusive Events in a Patient With Chronic Myeloid Leukemia Treated With Ponatinib by Osamu Imataki, Makiko Uemura (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11576327.txt.
Description
Osamu Imataki and Makiko Uemura report artery-blocking events in a leukemia patient treated with ponatinib in a 2024 case report. Such events are a rare but known hazard of this targeted drug class.
The forty-seven-year-old woman had chronic myeloid leukemia that failed two earlier targeted drugs over thirty months. Ponatinib finally drove her disease into complete molecular remission after twenty-eight months. Then imaging showed narrowing of both middle cerebral arteries, the vessels feeding much of each brain hemisphere. The pair note the lesion sites were atypical, not the spots ordinary artery hardening favors. The case warns that vascular checks belong in long-term ponatinib care.
Catalog record
| CREATOR | Osamu Imataki, Makiko Uemura |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 5 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |