Chloroquine-primaquine therapeutic response and safety in patients with uncomplicated Plasmodium vivax malaria in the Colombian Amazon region
Paula Calderón-Ruiz, Gabriel Velez-Tobón, Sebastian Bolívar-Hernández, Luz Mila Murcia-Montaño, Alberto Tobón-Castaño · 2024
Read Chloroquine-primaquine therapeutic response and safety in patients with uncomplicated Plasmodium vivax malaria in the Colombian Amazon region by Paula Calderón-Ruiz, Gabriel Velez-Tobón, Sebastian Bolívar-Hernández, Luz Mila Murcia-Montaño, Alberto Tobón-Castaño (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11575219.txt.
Description
Paula Calderón-Ruiz and co-authors test the standard two-drug cure for vivax malaria in the Colombian Amazon, in a 2024 trial. Vivax malaria is the milder but stubborn form of the disease, prone to return. Local proof that the chloroquine plus primaquine pairing still works was thin. The team ran a trial at three sites in the Amazonas region.
Just over one hundred patients took the pairing, with primaquine given for seven days or fourteen. Some took their doses under watch, and others on their own. At 28 days, watched patients in both arms all responded well. Unwatched patients did slightly worse, though still near nine in ten or better. No bad side effects turned up. The authors back the pairing, with a call for watching doses in the region.
Catalog record
| CREATOR | Paula Calderón-Ruiz, Gabriel Velez-Tobón, Sebastian Bolívar-Hernández, Luz Mila Murcia-Montaño, Alberto Tobón-Castaño |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |