Three-Component 1,2-Dioxygenation of 1,3-Dienes Using Carboxylic Acids and TEMPO
Sophia · 2024
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Description
A research team published a chemistry paper in 2024 on a mild way to add two oxygen groups across one double bond of diene molecules, all without metals. They used a stable radical reagent and simple carboxylic acids as the oxygen source. The reaction worked across many dienes and acids, both fatty and ring-based.
The oxygens landed in exactly one spot pattern every time. The team then showed how each of the two new groups can be changed on its own, including trimming the leftover double bond to reach fully saturated building blocks. Lab and computer evidence agreed on how the acid drives the reagent to split and react.
Catalog record
| CREATOR | Sophia |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |