The association between metabolic syndrome and lung cancer risk: a Mendelian randomization study
Zhicheng Wei, Yunyun Hu, Fang Zuo, Xiushu Wen, Desheng Wu, Xiaodong Sun, Conghai Liu · 2024
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Description
Zhicheng Wei and six co-authors use genetics to test whether a cluster of health problems raises lung cancer risk. The cluster, called metabolic syndrome, ties together weight, blood sugar, blood pressure, and blood fats. Plain studies cannot prove cause, so the team used a method that treats gene variants as a natural test. They drew on large public gene databases.
The syndrome raised the odds of lung cancer overall, and most clearly of two types: squamous cell and small cell. It showed no clear link to a third type. Smoking, drink, weight, schooling, and diabetes may carry part of the effect. The paper adds gene-based weight to the case for prevention.
Catalog record
| CREATOR | Zhicheng Wei, Yunyun Hu, Fang Zuo, Xiushu Wen, Desheng Wu, Xiaodong Sun, Conghai Liu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |