Adoptive T cell therapies for solid tumors: T(I)ME is of the essence
Nour Amwas, Chu-Hsuan Chiu, Diana Gumber, Leo D. Wang · 2024
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Description
Amwas and three co-authors wrote a review in twenty twenty-four on adoptive T cell therapy for solid tumors. In these treatments, a patient's own immune cells are collected, changed or grown in a lab, and given back to fight cancer. The authors focus on why solid tumors, such as brain tumors, resist such care.
The review compares three main types: tumor-infiltrating lymphocyte therapy, engineered receptor therapy, and CAR T cell therapy. Each type has strengths, such as hitting many tumor targets or sensing very low levels of a target. The authors then survey ways to help cells reach tumors, stay active, and work inside the harsh space around a tumor.
Catalog record
| CREATOR | Nour Amwas, Chu-Hsuan Chiu, Diana Gumber, Leo D. Wang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 8 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |