Serum neurofilament light and glial fibrillary acidic protein levels are not associated with wearing-off symptoms in natalizumab-treated multiple sclerosis patients
Alyssa A Toorop, Mark HJ Wessels, Lynn Boonkamp, Liza MY Gelissen, E Hoitsma, Esther MPE Zeinstra, Luuk C van Rooij, Caspar EP van Munster, Anke Vennegoor, Jop P Mostert, Beatrijs HA Wokke, Nynke F Kalkers, Erwin LJ Hoogervorst, Jeroen JJ van Eijk, Christiaan M Roosendaal, Jolijn J Kragt, Marijke Eu · 2024
Read Serum neurofilament light and glial fibrillary acidic protein levels are not associated with wearing-off symptoms in natalizumab-treated multiple sclerosis patients by Alyssa A Toorop, Mark HJ Wessels, Lynn Boonkamp, Liza MY Gelissen, E Hoitsma, Esther MPE Zeinstra, Luuk C van Rooij, Caspar EP van Munster, Anke Vennegoor, Jop P Mostert, Beatrijs HA Wokke, Nynke F Kalkers, Erwin LJ Hoogervorst, Jeroen JJ van Eijk, Christiaan M Roosendaal, Jolijn J Kragt, Marijke Eu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11568651.txt.
Description
Alyssa Toorop and co-authors test whether two blood marks track the fade of a drug's effect in multiple sclerosis. The study appeared in 2024. Many patients feel the drug wear off near the next dose. The marks show nerve and support cell harm, which might explain the fade.
Over three hundred trial patients gave blood and filled forms on the fade. More than half felt the fade at some point in care. Blood mark levels did not track the fade at any time point. Start levels also failed to guess who would feel the fade first. The team says fresh and long nerve harm most apt do not cause the fade.
Catalog record
| CREATOR | Alyssa A Toorop, Mark HJ Wessels, Lynn Boonkamp, Liza MY Gelissen, E Hoitsma, Esther MPE Zeinstra, Luuk C van Rooij, Caspar EP van Munster, Anke Vennegoor, Jop P Mostert, Beatrijs HA Wokke, Nynke F Kalkers, Erwin LJ Hoogervorst, Jeroen JJ van Eijk, Christiaan M Roosendaal, Jolijn J Kragt, Marijke Eu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 12 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |