Advances in Trop-2 targeted antibody-drug conjugates for breast cancer: mechanisms, clinical applications, and future directions

Yujun Tong, Xiaobing Fan, Huan Liu, Tiantian Liang · 2024

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Description

Breast cancer remains a leading cause of cancer-related deaths among women worldwide, highlighting the need for novel therapeutic strategies. Trophoblast cell surface antigen 2 (Trop-2), a type I transmembrane glycoprotein highly expressed in various solid tumors including all subtypes of breast cancer, has emerged as a promising target for cancer therapy.

Catalog record

CREATORYujun Tong, Xiaobing Fan, Huan Liu, Tiantian Liang
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE73 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11563829

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