Selective placement of functionalised DNA origami via thermal scanning probe lithography patterning†
Tingting Zheng, Caoimhe O’Neill, John F. Marshall, Thomas Iskratsch, Matteo Palma · 2024
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Description
DNA origami folds a long strand of DNA into tiny shapes that can carry cargo, and placing each one exactly where it belongs is the hard part. Tingting Zheng, Caoimhe O'Neill, John Marshall, Thomas Iskratsch, and Matteo Palma use a heated scanning probe to pattern a surface so the folded shapes stick only at chosen spots. As a proof of concept they placed origami carrying gold particles and quantum dots, tiny light-emitting crystals.
The shapes landed at the planned positions in neat arrays, with control down to single molecules. The team says the method could build mixed arrays where different spots carry different cargo. Such platforms could serve in sensing and in the study of single molecules and new materials.
Catalog record
| CREATOR | Tingting Zheng, Caoimhe O’Neill, John F. Marshall, Thomas Iskratsch, Matteo Palma |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |