Towards the Development of an Optical Biosensor for the Detection of Human Blood for Forensic Analysis
Hayley Costanzo, Maxine den Hartog, James Gooch, Nunzianda Frascione · 2024
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Description
Costanzo and co-authors work in 2024 on a light based sensor that can spot human blood at crime scenes without harming the sample. Current quick tests can mistake other fluids for blood and can spoil later DNA work. Their sensor uses short DNA strands that bind tightly to red blood cells.
The design pairs gold specks with tagged DNA strands that glow when freed. When red cells are present, the strands break away and the glow returns. Two blood binding strands were chosen for the design. The team tuned how strands join the gold, pair with tags, and break free, and they saw the glow return as hoped in tests.
Catalog record
| CREATOR | Hayley Costanzo, Maxine den Hartog, James Gooch, Nunzianda Frascione |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |