Molecular and Cellular Mechanisms Involved in the Pathophysiology of Retinal Vascular Disease—Interplay Between Inflammation and Oxidative Stress

Jovana V. Srejovic, Maja D. Muric, Vladimir Lj. Jakovljevic, Ivan M. Srejovic, Suncica B. Sreckovic, Nenad T. Petrovic, Dusan Z. Todorovic, Sergey B. Bolevich, Tatjana S. Sarenac Vulovic · 2024

Read Molecular and Cellular Mechanisms Involved in the Pathophysiology of Retinal Vascular Disease—Interplay Between Inflammation and Oxidative Stress by Jovana V. Srejovic, Maja D. Muric, Vladimir Lj. Jakovljevic, Ivan M. Srejovic, Suncica B. Sreckovic, Nenad T. Petrovic, Dusan Z. Todorovic, Sergey B. Bolevich, Tatjana S. Sarenac Vulovic (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11546760.txt.

Description

Jovana Srejovic and co-authors review diseases of the retina's blood vessels in this 2024 paper. The group covers diabetic eye disease, disease in early-born infants, age-related macular change, and blocked retinal vessels. All share harm to the network of vessels that feeds the retina. The review traces the signal paths that drive these diseases. It highlights key molecules and how they interact with each other. One growth factor stands at the center of faulty new vessel growth.

Drugs that block that factor are now the most successful treatment for these disorders. Swelling signals and damage from oxygen stress also play major roles. Their interplay with vessel growth is a focus of the review. The authors aim to give researchers a map of targets for new drugs. The piece is a synthesis of past studies, not a new experiment. It spans both lab findings and clinic use.

Catalog record

CREATORJovana V. Srejovic, Maja D. Muric, Vladimir Lj. Jakovljevic, Ivan M. Srejovic, Suncica B. Sreckovic, Nenad T. Petrovic, Dusan Z. Todorovic, Sergey B. Bolevich, Tatjana S. Sarenac Vulovic
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE67 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11546760

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