Blood-Based Biomarkers in Frontotemporal Dementia: A Narrative Review
Ioannis Liampas, Panagiota Kyriakoulopoulou, Vasiliki Karakoida, Panagiota Andriana Kavvoura, Markos Sgantzos, Dimitrios P Bogdanos, Polyxeni Stamati, Efthimios Dardiotis, Vasileios Siokas, Katrin Beyer · 2024
Read Blood-Based Biomarkers in Frontotemporal Dementia: A Narrative Review by Ioannis Liampas, Panagiota Kyriakoulopoulou, Vasiliki Karakoida, Panagiota Andriana Kavvoura, Markos Sgantzos, Dimitrios P Bogdanos, Polyxeni Stamati, Efthimios Dardiotis, Vasileios Siokas, Katrin Beyer (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11546606.txt.
Description
Ioannis Liampas and co-authors review blood markers for frontotemporal dementia. Their 2024 review sorts which tests help and which do not. This dementia attacks behavior and language, and can mimic mental illness. Blood tests would be cheaper and kinder than scans or spinal taps.
One marker, neurofilament light chain, stands out. It helps separate the disease from psychiatric look-alikes and tracks decline. Its heavy-chain cousin may flag the turn into full dementia. A marker called progranulin can spot carriers of one gene fault. Total tau disappoints, though its altered form may help against Alzheimer's confusion. A protein named TDP-43 looks promising for diagnosis. The review maps a fast-moving test menu.
Catalog record
| CREATOR | Ioannis Liampas, Panagiota Kyriakoulopoulou, Vasiliki Karakoida, Panagiota Andriana Kavvoura, Markos Sgantzos, Dimitrios P Bogdanos, Polyxeni Stamati, Efthimios Dardiotis, Vasileios Siokas, Katrin Beyer |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |