Impact of Tigecycline on Coagulation in Severe Infections and Effect of Vitamin K1 Intervention: A Retrospective Single-Center Analysis
Haiyan Sun, Xianqing Meng, Xupeng Shao, Liyun Duan, Kailiang Fan · 2024
Read Impact of Tigecycline on Coagulation in Severe Infections and Effect of Vitamin K1 Intervention: A Retrospective Single-Center Analysis by Haiyan Sun, Xianqing Meng, Xupeng Shao, Liyun Duan, Kailiang Fan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11542504.txt.
Description
Haiyan Sun and four co-authors study clotting harm from a strong antibiotic in a paper from two thousand twenty-four. Tigecycline treats stubborn bacterial infections, but bleeding is a known dose-linked side effect. The team reviewed its use at one hospital over six years.
Of nine hundred twenty patients, about twenty-four percent developed a clotting disorder. Problems tended to appear five to seven days into treatment. High-dose patients fared worse on clotting times and fibrinogen levels than normal-dose patients. Seventy-two patients received vitamin K1, after which clotting measures improved in both dose groups. The authors conclude the harm grows with dose and time, and that vitamin K1 can correct it.
Catalog record
| CREATOR | Haiyan Sun, Xianqing Meng, Xupeng Shao, Liyun Duan, Kailiang Fan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |