Tooth-Binding Graphene Quantum Dots Silver Nanocomposites for Prevention of Dental Caries
Iris Xiaoxue Yin, John Yun Niu, May Lei Mei, Jinyao Tang, William Ka Kei Wu, Chun Hung Chu · 2024
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Description
Iris Xiaoxue Yin and five co-authors engineer a nanomaterial that sticks to teeth, kills cavity bacteria, and rebuilds mineral at the same time. Silver nanoparticles fight Streptococcus mutans but can stain teeth and wander off. Anchoring silver to graphene quantum dots functionalized with alendronate, a bone-seeking drug fragment, aims the particles at tooth mineral.
The composite was characterized by electron microscopy and spectroscopy, then tested for toxicity against gum fibroblasts and tooth stem cells. Binding to hydroxyapatite was measured directly. Antibacterial power against the cavity bacterium was checked by imaging and colony counts. Finally, mineral regrowth on human dentine was assessed by micro-CT and microscopy. The work targets prevention that stays where it is painted.
Catalog record
| CREATOR | Iris Xiaoxue Yin, John Yun Niu, May Lei Mei, Jinyao Tang, William Ka Kei Wu, Chun Hung Chu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |