Plasmid-encoded phosphatase RapP enhances cell growth in non-domesticated Bacillus subtilis strains
Manlu Zhu, Yiheng Wang, Haoyan Mu, Fei Han, Qian Wang, Yongfu Pei, Xin Wang, Xiongfeng Dai · 2024
Read Plasmid-encoded phosphatase RapP enhances cell growth in non-domesticated Bacillus subtilis strains by Manlu Zhu, Yiheng Wang, Haoyan Mu, Fei Han, Qian Wang, Yongfu Pei, Xin Wang, Xiongfeng Dai (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11538241.txt.
Description
Manlu Zhu and seven co-authors study a plasmid gene in Bacillus subtilis in a paper from two thousand twenty-four. Lab strains of this bacterium lost a large plasmid during domestication. The plasmid carries a gene for a phosphatase, RapP, which controls biofilm formation and spore making.
The team found the plasmid, and the gene in particular, raise growth rates in wild-type strains. The gene blocks an early start of the adaptive response during fast growth. That frees cell resources for growth-promoting pathways instead. Fitness in the stationary phase was not harmed. The authors say the gene helps the bacterium balance growth against survival traits, easing a classic trade-off in microbe life.
Catalog record
| CREATOR | Manlu Zhu, Yiheng Wang, Haoyan Mu, Fei Han, Qian Wang, Yongfu Pei, Xin Wang, Xiongfeng Dai |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |