Effects of cold stress on the blood-brain barrier in Plectropomus leopardus
Yilan Guo, Cun Wei, Hui Ding, Peiyu Li, Yurui Gao, Kangning Zhong, Zhenmin Bao, Zhe Qu, Bo Wang, Jingjie Hu · 2024
Read Effects of cold stress on the blood-brain barrier in Plectropomus leopardus by Yilan Guo, Cun Wei, Hui Ding, Peiyu Li, Yurui Gao, Kangning Zhong, Zhenmin Bao, Zhe Qu, Bo Wang, Jingjie Hu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11536950.txt.
Description
Yilan Guo leads a team of eleven authors chilling a valuable tropical fish to watch its blood-brain barrier respond. The leopard coral grouper is prized commercially but cold-sensitive, and its low-temperature biology is little studied. Six-month-old fish were cooled from twenty-five to thirteen degrees within a day, then allowed to rewarm naturally.
Serum hormones, enzyme activity, and brain gene expression were tracked through the cycle. The fish first coped by quieting their activity. Changed genes clustered in blood-brain barrier, inflammation, and blood-clotting pathways. A barrier gene, claudin 15a, was confirmed by tissue staining to respond to the cold. The work maps an early molecular alarm system relevant to aquaculture in variable climates.
Catalog record
| CREATOR | Yilan Guo, Cun Wei, Hui Ding, Peiyu Li, Yurui Gao, Kangning Zhong, Zhenmin Bao, Zhe Qu, Bo Wang, Jingjie Hu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |