Construction of a Wilms tumor risk model based on machine learning and identification of cuproptosis-related clusters

Jingru Huang, Yong Li, Xiaotan Pan, Jixiu Wei, Qiongqian Xu, Yin Zheng, Peng Chen, Jiabo Chen · 2024

Read Construction of a Wilms tumor risk model based on machine learning and identification of cuproptosis-related clusters by Jingru Huang, Yong Li, Xiaotan Pan, Jixiu Wei, Qiongqian Xu, Yin Zheng, Peng Chen, Jiabo Chen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11536559.txt.

Description

Jingru Huang and seven co-authors build a risk model for a child kidney tumor in a 2024 study. The tumor, called Wilms tumor, is the most common kidney cancer of childhood. A fresh-found form of cell death, set off by copper, may shape how the tumor grows, but its inner role was murky.

The team pulled four gene data sets from a shared bank and scanned genes tied to the copper death path. From 105 tumor samples they found groups with like gene marks. They then built a learning model to sort risk, and mapped immune cells in each group. The work may guide care picks.

Catalog record

CREATORJingru Huang, Yong Li, Xiaotan Pan, Jixiu Wei, Qiongqian Xu, Yin Zheng, Peng Chen, Jiabo Chen
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11536559

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