Prevalence of molecular markers of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from West Africa during 2012–2022

Ruimin Zhou, Suhua Li, Penghui Ji, Shucheng Ruan, Ying Liu, Chengyun Yang, Dan Qian, Zhiquan He, Dan Wang, Deling Lu, Hongwei Zhang, Yan Deng · 2024

Read Prevalence of molecular markers of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from West Africa during 2012–2022 by Ruimin Zhou, Suhua Li, Penghui Ji, Shucheng Ruan, Ying Liu, Chengyun Yang, Dan Qian, Zhiquan He, Dan Wang, Deling Lu, Hongwei Zhang, Yan Deng (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11535326.txt.

Description

Ruimin Zhou and co-authors track drug resistance marks in malaria parasites from West Africa in a 2024 study. A drug pair used to shield people from malaria is losing force as parasite genes change. Samples came from cases imported to Henan Province, China, over a decade.

More than five hundred parasite samples were checked at two resistance genes. Mutant forms were near universal, with a few key changes at high rates in every country sampled. One strong resistance mark stayed rare overall but ran high in Liberia. A partly resistant pattern dominated, while the fully resistant pattern stayed uncommon.

Catalog record

CREATORRuimin Zhou, Suhua Li, Penghui Ji, Shucheng Ruan, Ying Liu, Chengyun Yang, Dan Qian, Zhiquan He, Dan Wang, Deling Lu, Hongwei Zhang, Yan Deng
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11535326

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