Dayuan Yin alleviates symptoms of HCoV-229E-induced pneumonia and modulates the Ras/Raf1/MEK/ERK pathway
Rui Li, Wen Zhang, Bei Huang, Guotong Sun, Yifei Xie, Junke Song, Shumei Wang, Guanhua Du · 2024
Read Dayuan Yin alleviates symptoms of HCoV-229E-induced pneumonia and modulates the Ras/Raf1/MEK/ERK pathway by Rui Li, Wen Zhang, Bei Huang, Guotong Sun, Yifei Xie, Junke Song, Shumei Wang, Guanhua Du (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11534925.txt.
Description
Li and co-authors test a classic herbal formula against virus-driven lung disease in this 2024 mouse study. The formula, Dayuan Yin, has a long history in Chinese medicine for infections. The team infected mice with a mild human coronavirus and checked breathing, lung damage, virus levels, and immune signals after treatment.
Treated mice breathed better and showed less organ damage. Virus loads and three key fever signals fell in lung tissue, while a spleen measure of immune balance improved. The formula also raised one protective protein and quieted a chain of growth signals inside cells. The authors read this as both antiviral and immune-calming action worth further study.
Catalog record
| CREATOR | Rui Li, Wen Zhang, Bei Huang, Guotong Sun, Yifei Xie, Junke Song, Shumei Wang, Guanhua Du |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |