Advances in the roles and mechanisms of mesenchymal stem cell derived microRNAs on periodontal tissue regeneration

Jiaxiang Zhang, Liangrui Chen, Jialu Yu, Weidong Tian, Shujuan Guo · 2024

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Description

Jiaxiang Zhang, Liangrui Chen, Jialu Yu, Weidong Tian, and Shujuan Guo review tiny gene regulators from stem cells and their role in regrowing gum and tooth support tissue, in work from 2024. Gum disease is a top cause of tooth loss in adults, and standard care can not rebuild the lost support well.

The regulators are short RNA chains that stem cells release, often packed in small bubbles that shield them. In gum tissue they drive cell growth and sorting, new blood vessels, and cleanup of dead cells. They also calm swelling and keep cells from dying too soon. Being small and able to hit gene sets at once, they suit a cell-free therapy plan. The review maps their known roles and paths.

Catalog record

CREATORJiaxiang Zhang, Liangrui Chen, Jialu Yu, Weidong Tian, Shujuan Guo
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE53 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11533400

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