Single-cell proteomics delineates murine systemic immune response to blast lung injury

Long Li, Zhongrui Liu, Linqiang Tian, Sanqiao Yao, Lili Feng, Feng Lai, Kunxi Wang, Yue Zhang, Yanyan Li, Jinheng Wang, Wenjie Ren · 2024

Read Single-cell proteomics delineates murine systemic immune response to blast lung injury by Long Li, Zhongrui Liu, Linqiang Tian, Sanqiao Yao, Lili Feng, Feng Lai, Kunxi Wang, Yue Zhang, Yanyan Li, Jinheng Wang, Wenjie Ren (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11532540.txt.

Description

Blast lung injury is the harm done to lungs by an explosion, and it can affect the whole immune system. In a 2024 study, Long Li and co-authors used mice to map that wider response at the level of single cells. They tracked which immune cells changed after a gas blast and how the body began to recover over time.

The team found sharp shifts in several white blood cell types in the early phase of injury. Cells from the spleen helped supply new cells while bone marrow output rose later, during recovery. T cells also joined the response early. The map points to stages where immune care might help most.

Catalog record

CREATORLong Li, Zhongrui Liu, Linqiang Tian, Sanqiao Yao, Lili Feng, Feng Lai, Kunxi Wang, Yue Zhang, Yanyan Li, Jinheng Wang, Wenjie Ren
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE63 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11532540

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