A fast Monte Carlo cell-by-cell simulation for radiobiological effects in targeted radionuclide therapy using pre-calculated single-particle track standard DNA damage data
A. Lim, M. Andriotty, T. Yusufaly, G. Agasthya, B. Lee, C. Wang · 2023
Read A fast Monte Carlo cell-by-cell simulation for radiobiological effects in targeted radionuclide therapy using pre-calculated single-particle track standard DNA damage data by A. Lim, M. Andriotty, T. Yusufaly, G. Agasthya, B. Lee, C. Wang (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11460290.txt.
Description
Lim and five co-authors speed up cell-by-cell ray harm sims with a pre-made track bank in this twenty twenty-three paper. Such sims trace how ray cures scar DNA in each cell of a tumor. Full track math per cell is true yet far too slow for drug design runs.
Inside, lone-track harm files are made once and kept in a bank for reuse. Time stamps are hand-added to those files to catch dose-rate play. A cell-fate model then reads a drawn file and calls breaks, bad fixes, and death. Checks on break yield match lab facts from past work in the field. A test on tumor cells dosed with a ray drug gave scar counts in line with print.
Catalog record
| CREATOR | A. Lim, M. Andriotty, T. Yusufaly, G. Agasthya, B. Lee, C. Wang |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |