New frontiers in retinal transplantation

Francesco Saverio Sorrentino, Patrick Di Terlizzi, Francesco De Rosa, Carlo Salati, Leopoldo Spadea, Caterina Gagliano, Mutali Musa, Marco Zeppieri · 2024

Read New frontiers in retinal transplantation by Francesco Saverio Sorrentino, Patrick Di Terlizzi, Francesco De Rosa, Carlo Salati, Leopoldo Spadea, Caterina Gagliano, Mutali Musa, Marco Zeppieri (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11438945.txt.

Description

Francesco Saverio Sorrentino and co-authors review retinal transplantation in this 2024 paper. The approach aims to regrow damaged layers of the retina, the light-sensing part of the eye, by placing new cells where old ones have died. Even in late disease, many inner eye cells stay alive, which leaves a path for new light-sensing cells to reconnect.

The review covers stem cell sources, lab-grown retinal tissue, and frames that carry cells into place. The eye suits this work because it tends to accept grafts and needs few cells to work. The authors also weigh gene editing tools and the ethics of using embryonic stem cells. Most methods are still in early trials, and the authors stress that more testing is needed before sight gains are sure.

Catalog record

CREATORFrancesco Saverio Sorrentino, Patrick Di Terlizzi, Francesco De Rosa, Carlo Salati, Leopoldo Spadea, Caterina Gagliano, Mutali Musa, Marco Zeppieri
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE39 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11438945

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