Robotic right ventricle is a biohybrid platform that simulates right ventricular function in (patho)physiological conditions and intervention

Manisha Singh, Jean Bonnemain, Caglar Ozturk, Brian Ayers, Mossab Y. Saeed, Diego Quevedo-Moreno, Meagan Rowlett, Clara Park, Yiling Fan, Christopher T. Nguyen, Ellen T. Roche · 2023

Read Robotic right ventricle is a biohybrid platform that simulates right ventricular function in (patho)physiological conditions and intervention by Manisha Singh, Jean Bonnemain, Caglar Ozturk, Brian Ayers, Mossab Y. Saeed, Diego Quevedo-Moreno, Meagan Rowlett, Clara Park, Yiling Fan, Christopher T. Nguyen, Ellen T. Roche (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11343235.txt.

Description

Manisha Singh and ten co-authors build, in 2023 work, a soft robot copy of the heart's right pumping chamber. That chamber has drawn fresh focus in recent years, yet tools to test cures for it lag behind. Their model mixes a treated real inner lining with a soft robot muscle layer.

Hooked to a flow loop, the model copies real pressure and flow in health and in faults such as overload and weak squeeze. It also matches signs of chamber failure seen in a live pig test. The valve cords pull as in a real heart, so valve repair and swap can be tried on the bench. The team offers it as a test bed for new right-heart cures.

Catalog record

CREATORManisha Singh, Jean Bonnemain, Caglar Ozturk, Brian Ayers, Mossab Y. Saeed, Diego Quevedo-Moreno, Meagan Rowlett, Clara Park, Yiling Fan, Christopher T. Nguyen, Ellen T. Roche
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE77 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11343235

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