Effect of yeast probiotic Saccharomyces boulardii cell wall extract on Aspergillus fumigatus allergenicity in A549 cells
Donya Nikaein, Haleh Malekmadani, Babak Beikzadeh, Reza Mardanpour, Alireza Khosravi, Seyed Mohammad Moghadami · 2023
Read Effect of yeast probiotic Saccharomyces boulardii cell wall extract on Aspergillus fumigatus allergenicity in A549 cells by Donya Nikaein, Haleh Malekmadani, Babak Beikzadeh, Reza Mardanpour, Alireza Khosravi, Seyed Mohammad Moghadami (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11230140.txt.
Description
Nikaein and co-authors test in 2023 whether the cell wall of a probiotic yeast can blunt the allergen power of a common mold in lung cells. Interest in probiotics for airway allergy is growing. They challenged mold spores with yeast wall extract at varied doses.
The extract cut the mold's enzyme activity at higher doses and lowered expression of its main allergen gene at all doses tested. Lung cells exposed to mold plus extract were also checked for two inflammatory signal genes. The work suggests yeast wall parts may soften mold driven airway inflammation, a lead for allergy aid research.
Catalog record
| CREATOR | Donya Nikaein, Haleh Malekmadani, Babak Beikzadeh, Reza Mardanpour, Alireza Khosravi, Seyed Mohammad Moghadami |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |