What is a Bladder Cancer Molecular Subtype? – Counterpoint

François Radvanyi, Francisco X. Real, David McConkey · 2023

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Description

François Radvanyi, Francisco Real, and David McConkey wrote this 2023 counterpoint on what should count as a bladder cancer subtype. A companion paper argues that subtyping should rest mainly on the identity of the cancer cells themselves, and on the aim of the sorting. The three authors largely agree, but push the frame wider.

They argue that features which shift across place and time inside a tumor still carry clinical weight. The surroundings of the tumor, its mix of cell types, and how it evolves under treatment all shape what a patient faces. A useful classification, they say, should fold those moving parts in rather than freeze on cell identity alone. The exchange helps pathologists decide what their labels are really for.

Catalog record

CREATORFrançois Radvanyi, Francisco X. Real, David McConkey
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE15 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11165934

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