Glycine-rich peptides from fermented Chenopodium formosanum sprout as an antioxidant to modulate the oxidative stress

Chen-Che Hsieh, Shu-Han Yu, Hsing-Chun Kuo, Darin Khumsupan, Hsiao-Chu Huang, Yu-Wei Liou, Chen-Yu Kao, Szu-Chuan Shen, Kuan-Chen Cheng · 2023

Read Glycine-rich peptides from fermented Chenopodium formosanum sprout as an antioxidant to modulate the oxidative stress by Chen-Che Hsieh, Shu-Han Yu, Hsing-Chun Kuo, Darin Khumsupan, Hsiao-Chu Huang, Yu-Wei Liou, Chen-Yu Kao, Szu-Chuan Shen, Kuan-Chen Cheng (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10962670.txt.

Description

Chen-Che Hsieh and co-authors isolate a tiny peptide from fermented red quinoa sprouts and test it against oxidative stress, in a 2023 study. The sprouts were fermented with a fungus in a bioreactor, and one glycine-rich fragment from the smallest proteins showed strong antioxidant scores. Computer checks rated the peptide safe, non-toxic, and unlikely to trigger allergies.

Lab and simulation work then traced how it might calm particle-driven stress in cells. The peptide appears to block a key switch in the NF-kB pathway, dialing down the inflammatory response that follows. The authors present it as a food-derived candidate for easing oxidative stress, pending further tests.

Catalog record

CREATORChen-Che Hsieh, Shu-Han Yu, Hsing-Chun Kuo, Darin Khumsupan, Hsiao-Chu Huang, Yu-Wei Liou, Chen-Yu Kao, Szu-Chuan Shen, Kuan-Chen Cheng
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10962670

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