Application of the U.S. Food and Drug Administration’s Sentinel Routine Querying Tools to the Taiwan Sentinel Data Model-formatted National Health Insurance Research Database
Fang-Ju Lin, Ling-Ya Huang, Chi-Chuan Wang, Sengwee Toh · 2023
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Description
Fang-Ju Lin and colleagues test whether America's drug safety toolkit works on Taiwan's health records. The US Sentinel system watches insurance data for drug harms using shared tools and a common data layout. Taiwan rebuilt its national insurance database in that same layout.
The team reran four known drug-safety questions with the original designs and tools. Warfarin showed the expected higher bleeding risk, and a diabetes drug showed the expected low-blood-sugar risk. Two other associations came out weaker and not significant, plausibly from smaller numbers. The exercise proves safety methods can travel between health systems.
Catalog record
| CREATOR | Fang-Ju Lin, Ling-Ya Huang, Chi-Chuan Wang, Sengwee Toh |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |