NF-κB in biology and targeted therapy: new insights and translational implications

Qing Guo, Yizi Jin, Xinyu Chen et al. · 2024

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Description

Guo, Jin, Chen, and co-authors review NF-kB, a protein system known to science for nearly forty years. When found, it was seen mainly as a switch for inflammation, the body's response to harm. Long study since then has widened that picture a great deal.

The review gathers fresh insight into the many roles this system plays across biology. It then turns to drugs that aim to block or tune it, and to what that could mean for patients. Because the system touches inflammation, immunity, and cancer, a clear summary helps both basic researchers and drug developers.

Catalog record

CREATORQing Guo, Yizi Jin, Xinyu Chen et al.
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE285 KB
LICENSECreative Commons Attribution License
RIGHTSCC BY
SOURCEPubMed Central

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC10910037/

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