Relative effectiveness of bivalent COVID-19 vaccine: a systematic review and meta-analysis

Meng-qun Cheng, Rong Li, Zhi-ying Weng, Gao Song · 2024

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Description

Meng-qun Cheng, Rong Li, Zhi-ying Weng, and Gao Song pool the evidence on bivalent COVID-19 vaccines. These shots pair the original virus strain with a variant strain in one dose. Their 2023 review searched four databases through early November 2023 for trials and real-world studies. It then combined the results with a random-effects model, the standard way to average studies that differ. Quality of the non-random studies was scored with a common checklist.

How much extra protection the bivalent shot gives over earlier doses was the core question. Pooled numbers help health agencies decide who should get updated shots and when. The authors also flag where the evidence is thin or mixed. Their work sums up the first wave of studies on a vaccine rolled out at speed.

Catalog record

CREATORMeng-qun Cheng, Rong Li, Zhi-ying Weng, Gao Song
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE22 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10879625

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