Clinical evaluation of chitosan/polycaprolactone nanofibrous scaffolds releasing tetracycline hydrochloride in periodontal pockets of patients with chronic periodontitis
Janet Moradi Haghgoo, Parviz Torkzaban, Parisa Hashemi, Rana Sarvari, Sana Hashemi, Elahe Fakhri, Behnaz Alafchi · 2023
Read Clinical evaluation of chitosan/polycaprolactone nanofibrous scaffolds releasing tetracycline hydrochloride in periodontal pockets of patients with chronic periodontitis by Janet Moradi Haghgoo, Parviz Torkzaban, Parisa Hashemi, Rana Sarvari, Sana Hashemi, Elahe Fakhri, Behnaz Alafchi (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10862042.txt.
Description
Janet Moradi Haghgoo and co-authors test antibiotic fibre films placed inside gum pockets, in a 2023 trial. Gum disease is driven by bacteria, and swallowing antibiotics affects the whole body. A film that releases drug on the spot could treat deep pockets with fewer side effects.
Ten patients with deep pockets took part in a split-mouth trial, where one side got standard deep cleaning and the other got cleaning plus the film. Measures of pocket depth, tissue hold, and bleeding were taken at the start and after eight weeks. Both sides improved, but deep pockets on the film side improved more on all three measures. The authors call the film effective and free of side effects in this small test, while urging larger trials.
Catalog record
| CREATOR | Janet Moradi Haghgoo, Parviz Torkzaban, Parisa Hashemi, Rana Sarvari, Sana Hashemi, Elahe Fakhri, Behnaz Alafchi |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |