Neoadjuvant short-course radiotherapy or chemoradiation plus consolidative chemotherapy followed by radical operation for locally advanced rectal cancer
Shing Fung Lee, Pui Lam Yip, Barry Wo, Natalie Sean-Man Wong, Balamurugan A. Vellayappan, Harvey J. Mamon, Francis Ann Shing Lee · 2024
Read Neoadjuvant short-course radiotherapy or chemoradiation plus consolidative chemotherapy followed by radical operation for locally advanced rectal cancer by Shing Fung Lee, Pui Lam Yip, Barry Wo, Natalie Sean-Man Wong, Balamurugan A. Vellayappan, Harvey J. Mamon, Francis Ann Shing Lee (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10844885.txt.
Description
Two radiation plans before rectal surgery differ in length, and both now pair with added drug therapy. Shing Fung Lee and co-authors compared the plans in a study dated 2023 in the text. Records covered patients with locally advanced rectal cancer treated from 2013 to 2021. One plan gives a short burst of radiation, and the other a long course mixed with drugs. Both then add drug therapy before full surgery.
One hundred forty-four patients were found, and most went on to curative surgery. Full tumor clearance at surgery was modestly higher in the long-course group. Disease-linked failure ran lower for that group after adjustments. Three-year outcome curves are reported for both plans. Toxicity data round out the comparison for clinic use.
Catalog record
| CREATOR | Shing Fung Lee, Pui Lam Yip, Barry Wo, Natalie Sean-Man Wong, Balamurugan A. Vellayappan, Harvey J. Mamon, Francis Ann Shing Lee |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |