Efficacy of SGLT2 inhibitors in IgA nephropathy associated with alcoholic liver cirrhosis accompanied by nephrotic syndrome: a case report
Yusuke Yoshimura, Daisuke Ikuma, Hiroki Mizuno, Kei Kono, Keiichi Kinowaki, Hisashi Sugimoto, Hisashi Kamido, Yuichiro Sawada, Masato Mizuta, Shigekazu Kurihara, Yuki Oba, Masayuki Yamanouchi, Tatsuya Suwabe, Kenichi Ohashi, Yoshifumi Ubara, Naoki Sawa · 2024
Read Efficacy of SGLT2 inhibitors in IgA nephropathy associated with alcoholic liver cirrhosis accompanied by nephrotic syndrome: a case report by Yusuke Yoshimura, Daisuke Ikuma, Hiroki Mizuno, Kei Kono, Keiichi Kinowaki, Hisashi Sugimoto, Hisashi Kamido, Yuichiro Sawada, Masato Mizuta, Shigekazu Kurihara, Yuki Oba, Masayuki Yamanouchi, Tatsuya Suwabe, Kenichi Ohashi, Yoshifumi Ubara, Naoki Sawa (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10839058.txt.
Description
A case report from 2023 describes a fifty-one year old man with liver damage from alcohol who also had failing kidneys and heavy protein loss in his urine. Yusuke Yoshimura and co-authors found that a kidney biopsy showed IgA nephropathy, a disease where an immune protein builds up in the kidney. Standard steroid drugs were risky for this patient.
The team treated him with dapagliflozin, a drug first made for blood sugar, plus strict steps to stop drinking. Within one week his urine protein fell sharply, and no low blood sugar events occurred. The authors say the drug may offer a safer path when steroids are a poor fit. They also stress that one case cannot prove the treatment works for others.
Catalog record
| CREATOR | Yusuke Yoshimura, Daisuke Ikuma, Hiroki Mizuno, Kei Kono, Keiichi Kinowaki, Hisashi Sugimoto, Hisashi Kamido, Yuichiro Sawada, Masato Mizuta, Shigekazu Kurihara, Yuki Oba, Masayuki Yamanouchi, Tatsuya Suwabe, Kenichi Ohashi, Yoshifumi Ubara, Naoki Sawa |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |