Impact of different ANCA serotypes on the long-term outcome of ANCA-associated vasculitis patients
Fumin Qi, Jian Hao, Wei Wei · 2023
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Description
Fumin Qi, Jian Hao, and Wei Wei wrote this 2023 study of long-term outcomes in a blood vessel disease split by antibody type. In ANCA-associated vasculitis, the immune system attacks small vessels, and patients carry one of two main antibodies, against MPO or against PR3. Whether the type forecasts the future was the question.
The team followed 224 Chinese patients for almost four years on average. The MPO group was larger and older at diagnosis; the PR3 group had more ear, nose, and throat trouble. Disease activity and organ damage otherwise looked alike. Survival at five years was about fifty-six percent overall, and relapse-free survival about sixty-eight percent. Neither survival, relapse, nor remission depended on antibody type. The authors say treatment need not branch on serotype alone.
Catalog record
| CREATOR | Fumin Qi, Jian Hao, Wei Wei |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |