Integrating RNA-sequencing and network analysis to explore the mechanism of topical Pien Tze Huang treatment on diabetic wounds
Guang-Zhao Cao, Liang-Liang Tian, Jing-Yi Hou, Yi Zhang, He Xu, Hong-Jun Yang, Jing-Jing Zhang · 2024
Read Integrating RNA-sequencing and network analysis to explore the mechanism of topical Pien Tze Huang treatment on diabetic wounds by Guang-Zhao Cao, Liang-Liang Tian, Jing-Yi Hou, Yi Zhang, He Xu, Hong-Jun Yang, Jing-Jing Zhang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10826880.txt.
Description
Guang-Zhao Cao and colleagues present a two thousand twenty-three study of the traditional formula Pien Tze Huang applied to diabetic wounds. Diabetic ulcers heal slowly and cause much disability. Existing treatments fall short, prompting interest in this established remedy.
Diabetic rats with full-thickness wounds received the formula at two doses or a growth-factor drug. Treated wounds closed faster with richer collagen. Gene sequencing and network analysis traced the biological routes involved, backed by protein tests. The work gives a molecular account of how an old formula speeds repair, supporting controlled clinical evaluation.
Catalog record
| CREATOR | Guang-Zhao Cao, Liang-Liang Tian, Jing-Yi Hou, Yi Zhang, He Xu, Hong-Jun Yang, Jing-Jing Zhang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |