Associations of gestational diabetes and proton density fat fraction of vertebral bone marrow and paraspinal musculature in premenopausal women

Saori Harada, Alexandra S. Gersing, Yannick Stohldreier, Olaf Dietrich, Andreas Lechner, Jochen Seissler, Uta Ferrari, Eleni Pappa, Nina Hesse · 2024

Read Associations of gestational diabetes and proton density fat fraction of vertebral bone marrow and paraspinal musculature in premenopausal women by Saori Harada, Alexandra S. Gersing, Yannick Stohldreier, Olaf Dietrich, Andreas Lechner, Jochen Seissler, Uta Ferrari, Eleni Pappa, Nina Hesse (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10824991.txt.

Description

Saori Harada and co-authors scan bone and muscle fat in a 2023 study of younger women. A history of diabetes in pregnancy raises later risk of type 2 diabetes and broken bones. Fat stored inside bone marrow and back muscles, read by MRI as a fat fraction, may flag that risk early. The team studied women before menopause, focusing on spine bone marrow and the muscles that steady the spine.

No prior work had linked pregnancy diabetes history to these fat measures. The study sets out to test whether such links exist in this group. A clear link would give doctors a non invasive marker to watch in women whose pregnancies flagged metabolic strain. It could also guide early steps to protect bone strength long before menopause arrives.

Catalog record

CREATORSaori Harada, Alexandra S. Gersing, Yannick Stohldreier, Olaf Dietrich, Andreas Lechner, Jochen Seissler, Uta Ferrari, Eleni Pappa, Nina Hesse
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10824991

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