ROS-dependent catalytic mechanism of melatonin metabolism and its application in the measurement of reactive oxygen

Xiangge Tian, Xiaohui Kang, Fei Yan, Lei Feng, Xiaokui Huo, Houli Zhang, Yan Wang, Xia Lv, Xiaochi Ma, Jinsong Yuan, Jiao Peng, Li Dai · 2024

Read ROS-dependent catalytic mechanism of melatonin metabolism and its application in the measurement of reactive oxygen by Xiangge Tian, Xiaohui Kang, Fei Yan, Lei Feng, Xiaokui Huo, Houli Zhang, Yan Wang, Xia Lv, Xiaochi Ma, Jinsong Yuan, Jiao Peng, Li Dai (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10824942.txt.

Description

Xiangge Tian and co-authors published a chemistry study that the text dates to 2023; the catalog lists 2024. The study tracks how the body breaks down a sleep hormone made by the brain. How the hormone is broken down shapes how well it works. Its path in sick tissue was not fully known.

The team found sixteen breakdown products in cancer cells and in human liver tissue samples. Seven of the products were new to science. The main product in cancer cells differed from the main one in liver. It forms when reactive oxygen, a stress chemical, attacks the hormone. The team worked out the full step-by-step path of that change. They then used the product as a gauge of oxygen stress, even to test how well blood carries oxygen.

Catalog record

CREATORXiangge Tian, Xiaohui Kang, Fei Yan, Lei Feng, Xiaokui Huo, Houli Zhang, Yan Wang, Xia Lv, Xiaochi Ma, Jinsong Yuan, Jiao Peng, Li Dai
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10824942

Browse the full library · About the Tower of Babel