Air Pollution and Lung Cancer: Contributions of Extracellular Vesicles as Pathogenic Mechanisms and Clinical Utility
Jonathan González-Ruíz, Andrea ABaccarelli, David Cantu-de-Leon, Diddier Prada · 2023
Read Air Pollution and Lung Cancer: Contributions of Extracellular Vesicles as Pathogenic Mechanisms and Clinical Utility by Jonathan González-Ruíz, Andrea ABaccarelli, David Cantu-de-Leon, Diddier Prada (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10822800.txt.
Description
Jonathan González-Ruíz and co-authors review how the air itself may help cause lung cancer through tiny parcels cells mail to each other. Extracellular vesicles carry proteins and RNA between cells, and polluted lungs, cancerous or not, release them in altered loads. The review gathers evidence that these parcels can prime tissue for tumors, feed growth, and spread the havoc that inhaled particles begin.
That same traffic suggests a clinical opening. Vesicle cargo read from blood or breath could flag cancer early, and engineered vesicles might one day deliver drugs to the tumor. The authors stress how much of the chain, from particle exposure to vesicle release to tumor effect, remains unverified in people. They close with the studies most needed to turn mechanism into medicine.
Catalog record
| CREATOR | Jonathan González-Ruíz, Andrea ABaccarelli, David Cantu-de-Leon, Diddier Prada |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |