Stage-specific dynamic reorganization of genome topology shapes transcriptional neighborhoods in developing human retinal organoids
Zepeng Qu, Zachary Batz, Nivedita Singh, Claire Marchal, Anand Swaroop · 2023
Read Stage-specific dynamic reorganization of genome topology shapes transcriptional neighborhoods in developing human retinal organoids by Zepeng Qu, Zachary Batz, Nivedita Singh, Claire Marchal, Anand Swaroop (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10790351.txt.
Description
Zepeng Qu and four co-authors map how the fold of the gene string reshapes, stage by stage, as a lab-grown human eye part grows. Their study is from two thousand twenty-three.
The team built a fine map of the string's loops in the grown parts. Shifts of fold came with each stage, and they track the on-off of marks for each cell kind. Sets of genes slid twixt the string's live and quiet zones as they woke or slept. Eye-rich genes clump near loop bounds that fade. Their crowds sit in live zones, by switches for eye growth. Such maps bare how form steers the growth plan.
Catalog record
| CREATOR | Zepeng Qu, Zachary Batz, Nivedita Singh, Claire Marchal, Anand Swaroop |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 61 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |