Serum ferritin level is an effective prognostic factor for lung cancer immunotherapy
Fei Wang, Guodong Deng, Ning Liang, Pingping Hu, Kuo Liu, Tong Liu, Yang Li, Meng Yuan, Li Liu, Jian Xie, Lili Qiao, Fengjun Liu, Jiandong Zhang · 2023
Read Serum ferritin level is an effective prognostic factor for lung cancer immunotherapy by Fei Wang, Guodong Deng, Ning Liang, Pingping Hu, Kuo Liu, Tong Liu, Yang Li, Meng Yuan, Li Liu, Jian Xie, Lili Qiao, Fengjun Liu, Jiandong Zhang (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10783829.txt.
Description
Fei Wang and twelve co-authors published a 2023 study on blood ferritin as a predictor of lung cancer immunotherapy success. Ferritin stores iron in the body, and iron handling ties into ferroptosis, a cell death route that affects how immunotherapy works. A simple blood test that forecasts response would be valuable.
The team measured ferritin in 107 lung cancer patients before and during checkpoint inhibitor treatment. Patients who started with lower ferritin lived longer without their cancer progressing and had higher disease control rates. A fall in ferritin during treatment also tracked with better outcomes. The authors checked ferritin against tumor traits like stage and PD-L1 level. They propose ferritin as a cheap, routine prognostic marker.
Catalog record
| CREATOR | Fei Wang, Guodong Deng, Ning Liang, Pingping Hu, Kuo Liu, Tong Liu, Yang Li, Meng Yuan, Li Liu, Jian Xie, Lili Qiao, Fengjun Liu, Jiandong Zhang |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |