Applications of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) as a Genetic Scalpel for the Treatment of Cancer: A Translational Narrative Review

Riddhi Mondal, Niki Brahmbhatt, Sahibjot K Sandhu, Hetvi Shah, Mandeepsinh Vashi, Siddharth Kamal Gandhi, Priyansh Patel · 2023

Read Applications of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) as a Genetic Scalpel for the Treatment of Cancer: A Translational Narrative Review by Riddhi Mondal, Niki Brahmbhatt, Sahibjot K Sandhu, Hetvi Shah, Mandeepsinh Vashi, Siddharth Kamal Gandhi, Priyansh Patel (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10767422.txt.

Description

Mondal and six co-authors review CRISPR gene editing for cancer treatment, in work from twenty twenty-three. Cancer remains a global challenge with high death rates and heavy family burdens. CRISPR, borrowed from bacterial immune systems, can cut and edit genes with precision, like a genetic scalpel.

The translational narrative review covers how editing is being applied to cancer: fixing driver mutations, engineering immune cells, and finding drug targets. It weighs promise against delivery and safety hurdles. Reviews like this help clinicians and students see where editing is clinic ready and where it remains laboratory work.

Catalog record

CREATORRiddhi Mondal, Niki Brahmbhatt, Sahibjot K Sandhu, Hetvi Shah, Mandeepsinh Vashi, Siddharth Kamal Gandhi, Priyansh Patel
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE19 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10767422

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