Use of Proton Pump Inhibitors and Risk of Fracture in Adults: A Review of Literature
Yubraj Paudel, Beenish Najam, Heet N Desai, Janan Illango, Kofi D Seffah, Mahendar Kumar, Namballa Naveen, Vamsi Krishna Pachchipulusu, Sai Sri Penumetcha · 2023
Read Use of Proton Pump Inhibitors and Risk of Fracture in Adults: A Review of Literature by Yubraj Paudel, Beenish Najam, Heet N Desai, Janan Illango, Kofi D Seffah, Mahendar Kumar, Namballa Naveen, Vamsi Krishna Pachchipulusu, Sai Sri Penumetcha (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10760937.txt.
Description
Yubraj Paudel and co-authors review past work on stomach acid drugs and risk of bone fracture in adults. Their 2023 paper deals with proton pump inhibitors. These drugs are in common use for gut disorders. Reports have tied them to fractures. The review asks how strong that tie is, and in whom it holds.
Use of the drugs was tied to a shorter time to first fracture in adults aged twenty five and over. Overall risk of fracture was higher with use. Yet risk was not clearly higher in women over eighty or in patients with rheumatoid arthritis. In healthy men aged eighteen to fifty, no clear change in calcium or bone measures was seen. The authors urge caution in some patients. They note that lab proof for the risk is still lacking.
Catalog record
| CREATOR | Yubraj Paudel, Beenish Najam, Heet N Desai, Janan Illango, Kofi D Seffah, Mahendar Kumar, Namballa Naveen, Vamsi Krishna Pachchipulusu, Sai Sri Penumetcha |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |