PANoptosis in cancer, the triangle of cell death
Hantao Cai, Mingming Lv, Tingting Wang · 2023
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Description
Hantao Cai, Mingming Lv, and Tingting Wang review PANoptosis, a blended form of programmed cell death, and its place in cancer, in a 2023 article. Found in 2019, the process merges features of three older death routes: pyroptosis, apoptosis, and necroptosis, run together by a single complex called the PANoptosome. The review first lays out how each of the three works on its own, then shows how they interlock.
Regulatory networks that steer the combined process are mapped next. Links to many diseases, cancer among them, are already reported, though each tumor's use of the pathway is still being worked out. The authors present PANoptosis as a promising new angle for cancer therapy.
Catalog record
| CREATOR | Hantao Cai, Mingming Lv, Tingting Wang |
|---|---|
| YEAR | 2023 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |