Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer

Beverly Kyalwazi, Christina Yau, Michael J. Campbell, Toshio F. Yoshimatsu, A. Jo Chien, Anne M. Wallace, Andres Forero-Torres, Lajos Pusztai, Erin D. Ellis, Kathy S. Albain, Anne H. Blaes, Barbara B. Haley, Judy C. Boughey, Anthony D. Elias, Amy S. Clark, Claudine J. Isaacs, Rita Nanda, Hyo S. Han, · 2023

Read Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer by Beverly Kyalwazi, Christina Yau, Michael J. Campbell, Toshio F. Yoshimatsu, A. Jo Chien, Anne M. Wallace, Andres Forero-Torres, Lajos Pusztai, Erin D. Ellis, Kathy S. Albain, Anne H. Blaes, Barbara B. Haley, Judy C. Boughey, Anthony D. Elias, Amy S. Clark, Claudine J. Isaacs, Rita Nanda, Hyo S. Han, (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10755617.txt.

Description

A large team of co-authors presents a study from two thousand twenty-three on race, gene patterns, and outcomes in high-risk early breast cancer. Racial gaps in breast cancer outcomes are well known, yet genomic risk had rarely been examined by subtype with race in view. The authors set out to close that gap.

They used data from a multi-center trial of chemotherapy given before surgery, with added new agents. They checked how complete response and freedom from distant return of the cancer linked to race. They also tested whether gene expression signatures tracked with outcomes in the same way across racial groups.

Catalog record

CREATORBeverly Kyalwazi, Christina Yau, Michael J. Campbell, Toshio F. Yoshimatsu, A. Jo Chien, Anne M. Wallace, Andres Forero-Torres, Lajos Pusztai, Erin D. Ellis, Kathy S. Albain, Anne H. Blaes, Barbara B. Haley, Judy C. Boughey, Anthony D. Elias, Amy S. Clark, Claudine J. Isaacs, Rita Nanda, Hyo S. Han,
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10755617

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