Coronary artery calcification and plaque stability: an optical coherence tomography study

Zhifeng Qin, Li Yu, Yanwen Zhang, Qinglu Xu, Chao Li, Suhong Zhao, Xiangwen Xi, Yanan Tian, Zhao Wang, Jinwei Tian, Bo Yu · 2023

Read Coronary artery calcification and plaque stability: an optical coherence tomography study by Zhifeng Qin, Li Yu, Yanwen Zhang, Qinglu Xu, Chao Li, Suhong Zhao, Xiangwen Xi, Yanan Tian, Zhao Wang, Jinwei Tian, Bo Yu (2023) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-10750051.txt.

Description

Zhifeng Qin and co-authors ask whether calcium in a heart artery plaque makes it safer or more dangerous. Calcification marks hardened arteries, but its link to plaque rupture, the event behind most heart attacks, is disputed. Using optical coherence tomography, a light-based scan from inside the vessel, the team studied over four hundred patients with acute coronary syndrome, sorting plaques by calcium size.

Calcium appeared in about half of both culprit and bystander plaques. Small, spotty calcium traveled with more ruptures, more immune cells, and more cholesterol crystals. Large calcium also brought immune cells and crystals, though rupture linked more to the spotty kind. Broken plaques carried smaller calcium deposits overall. The shape and size of calcium, the authors conclude, matter as much as its presence.

Catalog record

CREATORZhifeng Qin, Li Yu, Yanwen Zhang, Qinglu Xu, Chao Li, Suhong Zhao, Xiangwen Xi, Yanan Tian, Zhao Wang, Jinwei Tian, Bo Yu
YEAR2023
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC10750051

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